High-Resolution Proteomics Unravel Architecture and Molecular Diversity of Native AMPA Receptor Complexes
نویسندگان
چکیده
منابع مشابه
High-Resolution Proteomics Unravel Architecture and Molecular Diversity of Native AMPA Receptor Complexes
AMPA-type glutamate receptors (AMPARs) are responsible for a variety of processes in the mammalian brain including fast excitatory neurotransmission, postsynaptic plasticity, or synapse development. Here, with comprehensive and quantitative proteomic analyses, we demonstrate that native AMPARs are macromolecular complexes with a large molecular diversity. This diversity results from coassembly ...
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ژورنال
عنوان ژورنال: Neuron
سال: 2012
ISSN: 0896-6273
DOI: 10.1016/j.neuron.2012.03.034